Skip to content
PeptidesFinder

Where to Buy PE-22-28: Vendor Comparison, Benefits & Side Effects

A mitochondrial peptide studied for neuroprotection.

Published December 17, 2025140 vendors listed2 cited sources
Compare 140 vendorsCompare prices — from $0.630/mgDose & cost calculator

Cheapest PE-22-28 prices per mg

The 5 lowest verified retail prices of 134 we track, ranked by cost per milligram.

Compare all 134 vendors →
PE-22-28 cost per milligram, cheapest retail vendors first
#VendorPrice / mgVisit vendor
1PrimeRx$0.630Visit
2Baicaoxiang Peptides$0.650Visit
3Steady Meds$0.790Visit
4PTSD Bioresearch$0.850Visit
5Hauxia Peptide$1.05Visit

Prices checked — the newest verification among the vendors shown. What “checked” means. Cost per milligram, normalised for comparison; confirm on the vendor’s own site before ordering. Sold for laboratory research use only.

What is PE-22-28?

PE-22-28 is a peptide fragment researched for its protective effects against oxidative stress.

Where to Buy PE-22-28 Online

140 vendors in our directory currently list PE-22-28 — 134 online stores and 6 wholesale suppliers. Stores sell by the vial with a price you can check; wholesale suppliers quote per gram on enquiry. Featured vendors paid for their placement; ratings and trust signals are never for sale.

The top 15 online stores are compared below, ordered by our directory ranking.

Compare all PE-22-28 prices per mg →

Some outbound links are affiliate links: purchases made through them may earn PeptidesFinder a commission at no extra cost to you.

Mechanism of Action

It stabilizes mitochondrial membranes and reduces apoptotic signaling.

Clinical Research

Cited studies

  1. 1TREK-1 channel blockade by Spadin (PE-22-28 parent) and its effects on depression
  2. 2PE-22-28: A potential antidepressant peptide targeting TREK-1 channels

Researched Benefits

Research on PE-22-28 has focused on the following areas:

  • Mitochondrial peptide fragment researched for protecting neurons from oxidative stress
  • May support mitochondrial membrane stability and reduce apoptosis in neural tissue
  • Investigated for neuroprotective effects in models of neurodegeneration

Side Effects & Safety

Adverse reactions and limitations documented for PE-22-28 include:

  • Limited human data
  • Unknown safety profile

Related Peptides

Other peptides researched in nootropics, anti-aging.

5-Amino-1MQ

  • Weight Loss
  • Anti-Aging
  • +1

A metabolic modulator studied for fat metabolism.

  • Weight Loss
  • Anti-Aging
  • Gut Health
Read the guide

Acetyl Hexapeptide-3

  • Skin, Hair & Beauty
  • Anti-Aging

A cosmetic peptide known for reducing the appearance of wrinkles.

  • Helps reduce the appearance of expression lines in cosmetic research
  • May relax superficial facial muscle contractions through SNARE interference
  • Supports smoother skin texture and visible wrinkle reduction
Read the guide

AHK

  • Skin, Hair & Beauty
  • Anti-Aging

A copper-binding peptide studied for skin and hair regeneration.

  • Supports collagen production and dermal remodeling in skin research
  • May promote hair follicle stimulation and scalp health
  • Investigated for improving skin firmness and visible signs of aging
Read the guide

Argireline

  • Skin, Hair & Beauty
  • Anti-Aging

A cosmetic peptide researched for reducing expression lines.

  • Helps reduce expression lines by modulating SNARE complex formation
  • May soften forehead and periorbital wrinkles in cosmetic applications
  • Supports smoother skin appearance without full neuromuscular blockade
Read the guide