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Where to Buy Melanotan 1: Vendor Comparison, Benefits & Side Effects

A peptide studied for pigmentation and photoprotection.

Published December 17, 2025135 vendors listed7 cited sources
Compare 135 vendorsCompare prices — from $0.420/mgDosing calculator

Cheapest Melanotan 1 prices per mg

The 5 lowest verified retail prices of 123 we track, ranked by cost per milligram.

Compare all 123 vendors →
Melanotan 1 cost per milligram, cheapest retail vendors first
#VendorPrice / mgVisit vendor
1Bio Bulk Peptides$0.420Visit
2Axtidebio$0.480Visit
3Topstide$0.630Visit
4Revive and Thrive RT$0.650Visit
5Biohacker Direct$0.810Visit

Prices checked — the newest verification among the vendors shown. What “checked” means. Cost per milligram, normalised for comparison; confirm on the vendor’s own site before ordering. Sold for laboratory research use only.

What is Melanotan 1?

Melanotan 1 is a synthetic analog of alpha-MSH researched for its ability to stimulate melanin production.

Where to Buy Melanotan 1 Online

135 vendors in our directory currently list Melanotan 1 — 123 online stores and 12 wholesale suppliers. Stores sell by the vial with a price you can check; wholesale suppliers quote per gram on enquiry. Featured vendors paid for their placement; ratings and trust signals are never for sale.

The top 15 online stores are compared below, ordered by our directory ranking.

Compare all Melanotan 1 prices per mg →

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Mechanism of Action

It activates melanocortin-1 receptors in melanocytes, increasing eumelanin synthesis.

Clinical Research

Cited studies

  1. 1Melanotan 1 (afamelanotide) in the treatment of erythropoietic protoporphyria

Further reading

Work this guide draws on. Listed without links because we hold no canonical URL for them — search the author and year to find the paper.

  • Sawyer TK, Hruby VJ, Hadley ME et al., 1980, PNAS — design of [Nle4, D-Phe7]-α-MSH; frog and lizard skin bioassays
  • Levine N, Sheftel SN, Eytan T et al., 1991, JAMA — subcutaneous [Nle4, D-Phe7]-α-MSH in human volunteers
  • Langendonk JG et al., 2015, New England Journal of Medicine — two randomised controlled trials of the afamelanotide implant in erythropoietic protoporphyria (approved indication)
  • Buscà R, Ballotti R, 2000, Pigment Cell Research — review of cAMP/MITF signalling in melanogenesis; cultured melanocytes
  • Kadekaro AL, Abdel-Malek ZA et al., 2005, Cancer Research — cultured human melanocytes; MC1R activation, oxidative stress and UV-induced DNA damage
  • European Medicines Agency (2014) and US FDA (2019) public assessment and approval documents for afamelanotide (SCENESSE) — regulatory review of the approved implant

Researched Benefits

Research on Melanotan 1 has focused on the following areas:

  • Alpha‑MSH analog studied for increasing skin pigmentation and photoprotection
  • May help reduce sunburn risk by darkening skin through melanocortin receptor activation
  • Investigated for potential effects on appetite and inflammation via melanocortin pathways

Side Effects & Safety

Adverse reactions and limitations documented for Melanotan 1 include:

  • Flushing
  • Nausea

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